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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
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Abstract

HERBAL EXTRACTION AND PLASMID CURING (CURING OF MULTIPLE DRUG RESISTANCE IN BACTERIA USING HERBAL EXTRACTS)

Jyoti A. Mohite, Yogini P. Soman and Shilpa S. Mujumdar*

ABSTRACT

Due to overuse of antibiotics to treat microbial infections,
microorganisms are becoming highly resistant to available antibiotics.
So Multiple Drug Resistance (MDR) is a serious, global and future
challenge to the chemotherapy or drug discovery programs. Genes
responsible for resistance to antibiotics are present in plasmid DNA.
Medicinal plants contain wide variety of active compounds such as
terpenoids, alkaloids, sulphur compounds, phenols, esters, aldehydes,
alcohols, glycosides, thymol are responsible not only for antibacterial,
antifungal, anti-helminth, antioxidants, anti-inflammatory activities but
also have R plasmid elimination property. So use of herbal extracts is
effective and efficient method as herbal compounds are safer to use
and not toxic like that of the chemical agents such as acridine orange,
ethidium bromide.

Keywords: terpenoids, alkaloids, sulphur compounds, phenols, esters, aldehydes, alcohols, glycosides, thymol.


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