WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

A REVIEW ON FACTS OF CD4 CELLS AND THEIR FUNCTIONS AND DIFFERENTIATION

S. Fayaz Ahammad*, A. Ramesh Babu, S.S. Somanathan, S. Mahaboob Basha, D. Ranganayakulu

ABSTRACT

CD4 cells are crucial in achieving a regulated effective immune response to pathogens. CD4 effector T cells, also called helper T (Th) cells, are the functional cells for executing immune functions. Balanced immune responses can only be achieved by proper regulation of the differentiation and function of Th cells. Dysregulated Th cell function often leads to inefficient clearance of pathogens and causes inflammatory diseases and autoimmunity. CD4 cells along with the CD8 cells make up the majority of T-lymphocytes. The cells after being activated and differentiated in to distinct effectors’ subtypes play a major role in mediating immune response through the secretion of specific cytokines. Unlike TH1 and TH2 cells which are considered to be terminally differentiated, TH17 and Treg have shown plasticity, there by suggesting that they are not terminally differentiated. The CD4 cells represent a unique branch of the adaptive immune system that is crucial in achieving a regulated effective immune response to pathogens and their proper functioning is vital for survival.

Keywords: CD4 Cell, Helper T cell, Autoimmunity, Immunization, Inflammatory disease.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More