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Abstract

EVALUATION OF ANTIBACTERIAL POTENTIAL AND PHYTOCHEMICAL STUDIES OF MANGIFERA INDICA L. LEAVES

Sneha S. Jaiswal*

ABSTRACT

The in vitro antibacterial activity of leaf extracts of Mangifera indica has been evaluated using disc diffusion method. Aqueous and ethanolic leaf extracts of Mangifera indica leaves were evaluated against pathogenic strains of four Gram negative bacteria Escherichia coli, Pseudomonas aeruginosa, Klebseilla pneumoniae and Salmonella typhi and two Gram positive bacteria Bacillus subtilis and Staphylococcus aureus. Ethanolic extract of Mangifera indica was found to be effective against Salmonella typhi, Staphylococcus aureus, Klebseilla pneumoniae and Pseudomonas aeruginosa, while its aqueous extract did not showed any activity against all the bacteria under study. Least effect of ethanolic extract was found on Bacillus subtilis and Escherichia coli. Thus, the ethanolic leaf extract of Mangifera indica was found to possess more antibacterial potential than its aqueous extract. Phytohemical tests showed the presence of alkaloids, carbohydrate, phenol, tannins, flavonoids and amino acid in the ethanolic portion of Mangifera indica leaves. These findings may open up the possibility of finding of new antimicrobial compound.

Keywords: Antibacterial activity, Mangifera indica, pathogenic strains, phytochemical studies.


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