WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

VALIDATED HPTLC ANALYSIS METHOD FOR QUANTIFICATION OF THYMOL CONTENT IN AJWAIN (TRACHYSPERMUM AMMI) FRUIT

Das Manosi *, Mondal D.N, Dutta Sreya, Mandal Achintya Kumar,
Ganguly Biplab and Hazra Jayram

ABSTRACT

A simple, sensitive and accurate HPTLC method has been develop and validated for the quantitative estimation of Thymol in Ajwain (Trachyspermum ammi) collected from local market.The method employed TLC Aluminum plate Precoated with silica gel 60F254 as stationary phase with mobile phase as Hexane : EtOAc (8:2; v/v). Thymol showed mean Rf value of 0.46 with ╬╗max at 278 nm. The method was validated in terms of linearity (200-600ng/spot) precision and accuracy (100.91% ) recovery. The Thymol content was found to be 330.63ng/gm in Trachyspermum ammi obtained from marketed sample. In this procedure, linearity (r2 =0.99998) ,limit of detection (50 ng/spot), limit of quantification (200 ng/spot) were found to be satisfactory. The proposed HPTLC method can be used for the quality control of the raw materials and for routine analysis.

Keywords: HPTLC, Validation, Thymol, Trachyspermum ammi, Quantification.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More