WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Shwetha K.*, S. Bharath and Sharon Furtado


Background: Periodontitis is an inflammatory response to bacteriological infections. The main objective of this study was to design a formulation for local delivery of chlorhexidine to the oral cavity for the management of chronic periodontitis. Chlorhexidine is a broad-spectrum biocide effective drug and chitosan is biodegradable polymer having broad spectrum antimicrobial activity are being selected as choice for formulation of periochip. Methods and Findings: Drug loaded periochips were prepared by solvent casting method employing mercury as a substrate and evaluated. Formulated periochips were found to be compatible with normal buccal mucosa within an acceptable pH range of 6.5 to 7. The results of drug content indicated that drug is uniformly dispersed into the periochips. The formulation with higher percentage of chitosan showed slower drug release when subjected to comparative in-vitro dissolution studies. The selected periochip formulations showed a broad spectrum of in-vitro antibacterial activity for an extended period of time. Conclusion: Chlorhexidine incorporated periochips was found to be stable, compatible with extended and better treatment of periodontitis having patient compliance.

Keywords: Chlorhexidine, Chitosan, Periodontitis, Periochip.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More