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Abstract

NEW ANALYTICAL METHOD DEVELOPMENT FOR LORNOXICAM AND THIOCOLCHICOSIDE IN SOLID DOSAGE FORM BY RP-HPLC METHOD

G. Saikiran* and Rakesh Kumar Jat

ABSTRACT

A simple, specific, accurate and precise Reverse Phase High Performance Liquid Chromatographic method was developed for estimation of Lornoxicam and Thiocolchicoside by Sunfire C18 (4.6×250mm) 5μ using mobile phase Methanol: Water (65:35% v/v) pH 4.0.The flow rate was 1.0 ml/min and effluent was monitored at 295nm. The retention time is 2.0min for Thiocolchicoside and 2.4 min for Lornoxicam respectively. Proposed method was optimized.

Keywords: Lornoxicam, Thiocolchicoside, HPLC.


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