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Abstract

BIOCHEMICAL MARKER ANALYSIS IN OBESE PATIENTS

Fadhil Hamad Zaidan,  Samer Salim Abed, *Balasubramanian Sathyamurthy

ABSTRACT

Obesity is a chronic medical disorder that can lead to diabetes, high blood pressure, heart disease and other chronic illnesses. It is difficult to treat and has a high relapse rate. The aim of our study is to assess the clinical and biochemical parameters related to obesity and Cardio Vascular Disorders risk factors in type 2 diabetics and its correlation with body weight. About 10 patients of different age groups were selected as experimental materials. The study was intended to study the important blood markers which can help to diagnose the severity of the obesity. The markers of interest were serum cholesterol, triglycerides and Vitamin B12 levels. Vitamin B12 is used as mode of treatment for the obese patients. All these are found to be positively correlated. Serum cholesterol is measured by spectrophotometry, Triglycerides by GPO/POD method and Vitamin B12 by chemiluminiscent immunoassay methods. The results obtained were found to be significantly correlative especially in the age group 31-35 followed by 16-20 age groups. The vitamin B12 levels were inversely proportional to the levels of the obese values. This is revealing that, Vitamin B12 is a limiting factor in obese patients and can be used as remedial measure. All the results were confirmed and significance was given by the student’s t test (p<0.05).

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