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Abstract

BIOCHEMICAL ALTERATIONS DUE TO AQUEOUS EXTRACT OF TINOSPORA CORDIFOLIA ON ALBINO RATS.

Gulzar Ahmad, Kusum Singh, Zamin Ahmad*, Mir Imran and Akhtar Rasool

ABSTRACT

Medicinal plants are staging a comeback and herbal renaissance all over the globe. Global estimates indicate that 80% of about four billion population cannot afford the products of the western pharmaceutical industry and have to rely upon the use of traditional medicines which are mainly derived from plant material. The present study is therefore designed to investigate the alterations in biochemical indices i.e. glycogen and protein content due to aqueous extract of Tinospora cordifolia at a dose level of 300mg/kg b.wt in normal rats of Wistar strain. The study was carried out by single and daily administration of dose for 7, 14, 21 and 28 days of duration. The results revealed significant alterations due to administration of aqueous extract of Tinospora cordifolia in glycogen as well as protein contents in liver due to chronic administration of the dose at the duration of 21 and 28 days.

Keywords: Tinospora cordifolia, Aqueous extract, Glycogen, Protein.


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