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Abstract

PHARMACOGNOSTIC AND PHYTOCHEMICAL EVALUATION OF MADHUKA ASWAGANDHADI CHOORNA - AN AYURVEDIC POLYHERBAL FORMULATION

Ashly Jose*, Chinchu Sara George, Devika Krishnan, Honey Haridas, Jayachandran T. P. and Bose R. C.

ABSTRACT

There are many traditional systems of medicine in the world, each with different associated philosophies and cultural origins. Ayurveda is one of the traditional medicinal systems of Indian. Due to the scientific advancement today, more and more pharmacologically active ingredients of the Ayurvedic medicines as well as their usefulness in drug therapy have been identified. Basically, it is the phytochemical constituent in the herbals which lead to the desired healing effect, such as saponins, tannins, alkaloids, alkenyl phenols, flavonoids, terpenoids, phorbol esters and sesquiterpenes lactones. A single herb may even contain more than one of the aforementioned phytochemical constituents, which works synergistically with each other in producing pharmacological action. In Ayurveda, single or multiple herbs (polyherbal) are used for the treatment. In this formulation of polyherbal formulation of Mwdhuka Aswagandhadi Choorna (Received from Kerala Ayurveda Limited, Athani, Ernakulam), Glycyrrhiza glabra L., Withania somnifera Dun., and Triphala are used. Preliminary quantitative analysis of the drug showed the presence of the alkaloids, proteins, tannins, phenolic compounds, athraquinon and saponin glycosides and carbohydrates. High extractive value indicates absence of exhausted materials, adulteration or incorrect processing during drying or storage of formulation. A low ash value is indicative of absence of contamination, substitution, adulteration or carelessness in preparing the formulation. The microscopic analysis of the drug showed the presence of disturbed pitted vessels, disturbed walls of fibres, starch grains, scleroids, in Yastimadhu; stone cells, scleroids, tannin in Bibheetaki; tannin, pitted stone cells in Haritaki; scleroids in Amlaki.

Keywords: Polyherbal, Madhuka aswagandhadi choorna, phytochemical, pharmacological evaluation.


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