WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

FRUCTOOLIGOSACCHARIDE INTAKE AFFECTS THE COLONIZATION OF S.MITIS ESTABLISHMENT IN ORAL CAVITY ALONG WITH GUT BACTERIA IN YOUNG SCHOOL CHILDREN OF URBAN VADODARA

Dr. Mini Sheth*, Harsha Hirdyani, Neha S. Lotankar and Fatema Bandukwala

ABSTRACT

Background: Streptococcus mitis are commensal bacteria that colonize hard surfaces in the oral cavity such as dental hard tissues as well as mucous membranes and are part of the oral flora. S.mitis is resistant to someantibiotics such as penicillin and cefotaxime and thus represent a potential clinical problem in the prevention of oral diseases. Due to the emergence of antibiotic resistance and frequent recolonization of treated sites with pathogenic bacteria, there was need for a new treatment paradigm to be introduced to periodontal disease. Objective: To determine the impact of Fructooligosaccharide supplementation on the establishment of S.mitis in mouth and Bifidobacteria, Lactobacilli and E.coli in the gut of children having fair oral hygiene status of urban Vadodara. Methods: 255 children (8- 12 years) were enrolled in the study from the Primary school of urban Vadodara and were assessed for their oral hygiene status, using Oral hygiene index-simplified. Sixty children having fair oral hygiene were purposively selected and grouped as experimental and control group. They were supplemented with, Fructooligosaccharide (FOS) incorporated buttermilk and plain buttermilk, for a period of 4 weeks. Pre data was collected on their basic oral hygiene practices using a structured questionnaire. Their saliva samples were analysed for the presence of S.mitis and stool samples in subsamples (n=30) were analysed for Bifidobacteria, Lactobacilli and E.coli, both at the baseline and after the intervention period. Results: The baseline data showed a strong association between oral hygiene status of children with age and gender as well as with establishment of S.mitis. Female children had poorer oral hygiene as compared to their male counter parts. Intervention brought about improvement in oral hygiene status in both the groups with the greater reduction in S.mitis counts (16.03%) in subjects of experimental group. Gut E.coli also significantly reduced (17.92%) upon supplementation with buttermilk+FOS along with a significant rise in Gut Bifidobacteria (11.58%) and Lactobacilli (11.58%). The oral hygiene status of the subjects significantly improved from fair to good (70.24%). Conclusion: Daily intake of 7g FOS with buttermilk and plain buttermilk helped to improve the oral hygiene status along with the improved beneficial gut microflora in children initially having fair oral hygiene status. The establishment of S.mitiswassignificantly reduced in both experimental and control groups.

Keywords: S.mitis, Bifidobacteria, Lactobacilli and E.coli.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More