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Abstract

A NOVEL PROCESS S-(-) AMLODIPINE AND THEIR INTERMEDIATES

Samatha S.*, Krishna MohanT. and Pradasaradhi M.

ABSTRACT

The present invention relates the new process for preparing for the S- (-) Amlodipine Besylate (S)-3-ethyl 5-methyl 2-[(2-aminoethoxy) methyl]- 4-(2-chlorophenyl)- 6-methyl -1, 4- dihydropyridine-3,5- dicarboxylatebenzenesulphonate) from Amlodipine base using L(+) Tartaric acid using solvent Iso propyl alcohol.

Keywords: Amlodipine base, S-(-) Amlodipine Besylate, L (+) Tartaric acid, Benzene sulfonic acid and Urea.


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