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Abstract

EVALUATION OF LETROZOLE INDUCED POLYCYSTIC OVARY SYNDROME (PCOS) USING ETHANOL AND ETHYL ACETATE EXTRACTS OF TECOMARIA CAPENSIS. (FAMILY: BIGNONIACEAE)

E. Tamil Jothi1*, CH. Harini2 and G. Nagarjuna Reddy

ABSTRACT

Polycystic ovary syndrome (PCOS) is a highly prevalent endocrinemetabolic
disorder that implies various severe consequences to female
health, including alarming rates of infertility. Ethanol extract of
Tecomeria capensis (Bignoniaceae) was investigated for the activity
against letrozole induced polycystic ovarian syndrome. Letrozole
induced PCO untreated rats exhibited a significant increase in body
weight compared to controls. In contrast, no further increase in body
weight was observed in ethanol extract of Tecomaria capensis treated
PCO rats. ethanol extract of Tecomaria capensis treatment in letrozole
induced PCO rats also demonstrated showed similar kinds of rhythm in
estrus cyclicity as controls and the metformin group suggesting reversion toward normal
physiology Letrozole treated PCO rats showed significant increases in ovarian weights
whereas ethanol extract of Tecomaria capensis treated PCO animals exhibited ovarian
weights similar to controls. Extract showed a significant results comparing to standards. Jeans
mai abh nahi loomgi. Badh.

Keywords: Tecomaria capensis, polycystic ovarian syndrome, letrozole.


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