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Abstract

PHYTOCHEMICAL SCREENING AND ANTIFUNGAL IMPLICATIONS OF CALOTROPIS PROCERA LEAF EXTRACTS USING VARIOUS SOLVENTS

H. Zaman*, R. M. Shrivastava, S. Shrivastava and S. Akther

ABSTRACT

Phytochemical screening of leaves of Calotropis procera is hereby reported. Antifungal activity of ethanol, chloroform and petroleum ether extracts of leaves of Calotropis procera on Aspergillus niger and Candida albicans were determined by nutrient agar well diffusion method. The results revealed that ethanol was the best extractive solvent for antifungal properties of leaves followed in order by Petroleum Chloroform and Petroleum (P<0.05). The ethanolic extracts of leaves of C. procera gave the widest zone of inhibition against Aspergillus niger and Candida. the growth of test fungi were inhibited by ethanolic extract while the chloroform and Petroleum ether was the least effective on the test fungi. The best antifungal activity was recorded in ethanol extract of C. procera than chloroform and Petroleum ether against Aspergillus niger and Candida albicans. This study revealed that the leaves of C.procera demonstrated strong inhibitory effect on the test organisms. The results therefore established a good support for the use of C.procera in traditional medicine.

Keywords: Antifungal activity, phytochemical ananlysis, Calotropis procera.


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