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Abstract

A REVIEW ON: Β-THALASSEMIA

Ramdas Malakar*, Manpreet Kour, S. N. Malviya and C. B. S. Dangi

ABSTRACT

The thalassemias represent the most common single gene disorder worldwide. The total annual incidence of symptomatic individuals with β-thalassemia is estimated at 1 in 100,000 throughout the world Thalassemias can't be prevented because they're inherited, "inherited" means they are passed on from parents to children. However, these bleeding disorders can be found before birth through prenatal tests. Thalassemia is a common inherited disease in the world. India accounts for 10% of the total world thalassemia population and approximately 1 in 30 in the general population is carrier of the mutated gene, so, it is important to take into consideration this disorder as it may prove deadly one. The intensity of this disorder can be lowered prenatal diagnosing and taking preventive measures. The present work summarizes β-thalassemia, epidemiology, causes and complication of this disorder.

Keywords: ?-thalassemia, ?-globin, epidemiology, etiology and complication.


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