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Abstract

ADVERSE DRUG REACTION: MONITORING MANAGEMENT AND DIAGNOSIS

*Shashi Pratap Singh, Suresh Chandra, Ashish Srivastava, Asfa Parveen, Rinki Yadav and Yogendra Pal

ABSTRACT

A harmful or significantly unpleasant effect caused by a drug at doses intended for therapeutic effect (or prophylaxis or diagnosis) which warrants reduction of dose or withdrawal of the drug and/or foretells hazard from future administration. If a drug has a narrow therapeutic range, samples can be taken to allow the dose to be adjusted so that the concentration remains between a minimum value for efficacy and a maximum value for safety. The diagnosis of an adverse drug reaction is part of the broader diagnosis in a patient, if a patient is taking medicines, the differential diagnosis should include the possibility of an adverse drug reaction the first problem is to find out whether a patient is taking a medicinal product, including: over-the-counter formulations; India has more than half a million qualified Doctors and15, 000 hospitals having bed strength of 6, 24,000. It is the fourth largest producer of pharmaceuticals in the world, it is emerging as an important Clinical trial hub in the world, many new drugs are being introduced in our country.

Keywords: Clinical trials, concentration, diagnosis, pharmaceuticals, medicines.


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