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R. Gowri*, N. Narayanan, A. Maheswaran, M. Vigneshwar, S. Velaravindan, V. Malathy


The word ‘Drug’ is obtained from Greek word droughe which means a herb. Drugs produce wide range of therapeutic effect and at the same time they may also produce adverse drug reaction. The adverse drug reaction may be long term or short time effect. Sometimes when a drug after proper approval and by clinical trials might produce perilous effect if administered to large population group. To counter these adverse effect wide range of testing are done. Pharmacovigilance is a pharmacological science which deals with the detection, assessment, understanding and prevention of adverse drug reaction. If adverse reaction outweighs the therapeutic effect then the drug should be banned from use. But there are some drug which banned in abroad still available easily in India. The prime reason behind it was the lack enforcement power of the regulatory body. There is alarming increase of irrational fixed dose combinations of drugs, also which eventually affects the quality of life of patients. This review throws an insight about the status of banned drugs by other countries owing to its severe adverse effects but available in India.

Keywords: Drug, adverse reaction, banned drug, Pharmacovigilance.

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