WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

FORMULATION, PHARMACEUTICAL PROPERTIES, CHRONOPHARMACOLOGY OF DICLOFENAC SODIUM WATER-INOIL- IN-WATER EMULSION BY USING TAIL IMMERSION METHOD

Pranav V. Khade*, Pratip K. Chaskar, Gaurav M. Doshi

ABSTRACT

Multiple emulsions, either w/o/w or o/w/o emulsions, are generally prepared using a two step procedure. Most knowledge of medication doses has been derived from single and multiple dose investigation following day time administration. Chronopharmacology studies involve the evaluation of such phenomenon after each of several different clock hours during day and night time. We have studied the analgesic effect of same dose of Diclofenac for testing at different hours by using tail immersion method. The project is undertaken to justify the influence of biological clock on the drug effectiveness, so as to improve the drug efficacy. It showed enhanced analgesic activity at afternoon (1200 h), evening (1800 h), and morning time (0600 h) as compared to the midnight (0000 h) time. Multiple emulsions showed the linear release or promising release characteristics of drug and also prolonged the action of drug.

Keywords:


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More