WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

EVALUATION OF ANTILITHIATIC ACTIVITY ON WHOLE PLANT OF MURRAYA KOENIGII.

Gajender Singh*, Nandlal Singh, Vihangesh Kumar Dixit, Vijay Kumar Singh, Dr. S.K. Prajapati

ABSTRACT

The ethanolic extract of whole plant of murraya koenigii Linn. was
evaluated for its antilithiatic activity in mices. Lithiasis was induced by
oral administration of ethylene glycolated water (0.75%) in adult male
Swiss albino mices for 28 days. The ionic chemistry of urine was
altered by ethylene glycol (EG), which elevated the urinary
concentration of crucial ions, viz. calcium, phosphorus and protein
thereby contributing to renal stone formation. However treatment with
ethanolic whole plant extract of murraya koenigii (200 and 300 mg /
kg body weight) in group III and IV significantly (p<0.05) reduced the
elevated level of these ions in urine. The levels of serum urea, uric acid
and creatinine were significantly increased (p < 0.05) in urolithiatic mices. Treatment with
plant extract restored the levels and it brought back the values to near normal range in
urolithiatic mices. All these observations revealed that ethanolic whole plant extract of
murraya koenigii has curative effect on stone formation induced by ethylene glycol.

Keywords: Antilithiatic, murraya koenigii, Ethylene glycol, Calcium, Phosphate and Protein.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More