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Abstract

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF AEROBIC GRAM NEGATIVE BACILLI FROM WOUND INFECTIONS IN DIABETIC PATIENTS

Dr. Ravishankar Reddy A*, M. Prathyusha, Dr. K. Saileela, Dr.V. Ramadevi, Dr. Srikanth, Dr. K. Kamal Chand.

ABSTRACT

All foot ulcers are colonized with potentially pathogenic organisms and Diabetic foot infections and ulcerations are more common in type 2 diabetes mellitus. Especially aerobic pathogens contributing to progressive and widespread tissue destruction, so we aimed to determine the common aerobic gram negative bacteria of diabetic wound infections and their in - vitro susceptibility to routinely used antibiotics after the Ethics Committee clearance. One hundred specimens from patients with diabetic wound infection were obtained and processed. Gramís staining, Culture, Biochemical reactions and antibiotic sensitivity testing was done. Results were tabulated and found that 96 samples were culture positive. 178 organisms were isolated from theses positive cultures. The most common isolate was P. aeruginosa 71(39.88%) followed by Escherichia coli 52 (29.2%) and K. pneumonia 46 (25.84%), showed good sensitivity to Gentamicin (68%), Cefipime (79%) and Amikacin (87%). The Imepenam was the most effective drug among multidrug resistant isolates. We conclude Diabetic foot infections are polymicrobial with predominance of Gram negative Pseudomonas aureginosa.

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