WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

FORMULATION, OPTIMIZATION AND EVALUATION OF ORAL ANTIBIOTIC FORMULATION TO INCREASE PEDIATRIC COMPLIANCE

Nandini Banerjee*, Sushma Singh

ABSTRACT

The objective of the current work was to formulate floating microspheres of cefpodoxime proxetil and then make them to orally disintegrating minitablet to increase the patient compliance amongst the Pediatric Patient Population. The antibiotic drug was coated with polymers HPMC K15 M and Ethyl Cellulose. The coat masked the bitter taste of the drug and also provided a sustained drug release over a period of 12hrs. This coated drug particles were then formulated into Orally dispersible Minitablets. The tablet batches were optimized for their dispersion time using different superdisintegrants at different concentrations. The superdisintegrants tried out were Crosscarmellose sodium and Sodium Starch Glycolate. The parameters evaluated included Hardness, Friability, dispersion time and in-vitro drug release over a period of 12hrs. The batches were also subjected to Stability study over a Period of 6 months at 450C/ 75% RH.

Keywords:


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More