Abstract

PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS IN ETHANOLIC LEAF EXTRACTS OF AGERATUM CONYZOIDES (L.)

A. Pauline Fatima Mary* and Dr. R. Sagaya Giri

ABSTRACT

Ageratum conyzoides L. (Family Asteraceae) is an annual herb with a long history of traditional medicinal use in the tropical and sub-tropical region of the world, commonly known as Billy gost weeds. In present study the ethanolic leaves extract of A. conyzoides have been evaluated using Gas Chromatography–Mass Spectrometry, while the mass spectra of the compounds found in the extracts were matched with the National Institute of Standards and Technology (NIST) library. To determine the bioactive components of ethanolic leaf extracts of A. conyzoides by GC-MS analysis were carried out. Twenty eight compounds were identified. Some important compounds are; 9- octadecanamide (27.24%), Phytol (5.92%), Phenol,4,6-di(1,1-dimethylethyl)2-methyl- (5.73%), Dibutyl phthalate (4.92%), Cyclopropane,1-methyl,2-octyl-(4.62%), Squalene (4.37%), á-Amyrin (4.06%) and Stigmasterol (3.08%). Some of the identified compounds have been reported to possess various biological activities such as antimicrobial, antioxidant, antiseptic, and anti-inflammatory.

Keywords: Ageratum conyzoides, bioactive components, ethanolic extract.