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Abstract

―FORMULATION DEVELOPMENT & EVALUATION OF FAST DISSOLVING TABLET OF RIZATRIPTAN BENZOATE”

Kishor Rodge*, R. S. Moon and Swapnil Waghmare

ABSTRACT

The purpose of this investigation was to to develop fast dissolving tablet of Rizatriptan Benzoate using various concentration of disintegrants and superdisintegrants along with directly compressible excipients. Rizatriptan benzoate use to treat migraines. Fast dissolving tablet of Rizatriptan benzoate containing crospovidone-xl, croscarmellose sodium, avicel PH-102, aspartame, magnesium Stearate, Aerosil, menthol, pearlitol SD-200 The formulation were evaluated for disintegration time, in vitro dissolution, hardness, friability, weight variation and thickness, water absorption ratio.

Keywords: superdisintegrant, Fast dissolving Tablet, Migraine, Rizatriptan benzoate.


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