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Abstract

TRIFLUOPERAZINE INDUCED DYSTONIA-A RARE CASE REPORT

Geethu C.*, Josna James, Jasmin Elizabeth Thomas, Elizabeth Phoeba Paul, Hemalatha S. and Sivakumar T.

ABSTRACT

Dystonia is a disorder characterized by involuntary muscle contractions that cause slow repetitive movements or abnormal postures which are painful. Drug-induced dystonic movements are caused by blockade of dopamine D2 receptors which are strongly associated with the efficacy of antipsychotics. Here we present a case of dystonia developed due to the use of typical antipsychotics. The first approach for treating acute dystonic reaction is reduction of the dosage or withdrawal of antipsychotics. Treatment strategies may also include switching from a First Generation Antipsychotics to a Second Generation Antipsychotics. Anticholinergic agents, dopamine agonists and benzodiazepines may often reduce the intensity of the acute dystonic reaction.

Keywords: Dystonia, Antipsychotics, Anticholinergics.


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