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Abstract

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITY OF LEAF AND BARK ETHANOL EXTRACTS OF MARINE AND TERRESTRIAL PLANTS OF XYLOCARPUS SPECIES.

Shaik Babu Saheb, Naragani Krishna, Shaik Ibrahim Khalivulla and Kokkanti Mallikarjuna*

ABSTRACT

True mangrove species of Xylocarpus belongs to meliaceae family and are distributed in the coastal ecosystems. Mangrove plants represent a unique set of plants with high adaptability to extreme environments. The unique adaptations of mangrove represent a rich source of bio active compounds. In the present work we report the anti-microbial activity of Xylocarpus grantum and Xylocarpus moluccensis. The antimicrobial activity of the leaf and bark of X.granatum and X.moluccensis were evaluated against antibiotic resistant bacteria and fungi like Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Eschrichia coli and Candida albicans. Ethanol extractions of leaf and bark were prepared using cold maturation and antimicrobial activity is evaluated by using agar well diffusion method. Marine and terrestrial plants of Xylocarpus granatum showed promising antibacterial activity against S.aureus (18mm), B.subtilis (15mm), B.cereus (18mm) and E.coli (21mm) and also antifungal activity against C. albicans (25mm) when compared to Xylocarpus moluccensis. The results indicated that Xylocarpus granatum is a potent source of bio active compounds when compared to Xylocarpus moluccensis.

Keywords: Xylocarpus granatum, Antimicrobial activity, Agar well diffusion method.


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