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Abstract

SHORT-TERM EXPOSURE TO NONYLPHENOL ALTERED MUSCULAR ANTIOXIDANT SYSTEM IN CICHLID FISH, ETROPLUS MACULATUS (BLOCH, 1795)

K. P. Asifa and K. C. Chitra*

ABSTRACT

Indigenous adult freshwater cichlid fish, Etroplus maculatus was used in the present study in order to assess the short-term effects of one of the environmental contaminants, nonylphenol in muscular tissue of fish. Treatment groups were exposed to nonylphenol at sublethal concentrations (one-fifth and one-tenth of LC50) for short-term duration, ie., 24, 72 and 96 h. Antioxidant parameters were analysed in muscle tissues of both control and treatment groups. Superoxide dismutase activity was significantly (P<0.05) increased at both concentrations in time-dependent manner when compared to control groups. However, the activities of catalase and glutathione reductase decreased significantly (P<0.05) with concomitant increase in the levels of hydrogen peroxide generation and lipid peroxidation in timedependent manner at both sublethal concentrations of nonylphenol. In addition the activity of one of the marker enzymes, alkaline phosphatase showed significant (P<0.05) reduction than that of control groups. The present observations clearly indicate that short-term exposure to nonylphenol altered muscular antioxidant system in fish and this could probably induced oxidative stress in muscle tissues of Etroplus maculatus.

Keywords: Nonylphenol, muscle, Etroplus maculatus, oxidative stress, ROS.


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