WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

ANTINOCICEPTIVE ACTIVITY OF METHANOL EXTRACT OF COMMELINA BENGHALENSIS LINN. WHOLE PLANT.

Tanvir Ahmad Chowdhury, Mohammad Shah Hafez Kabir*, Md. Ismail Hossain, Mohammed Farhad, Tanzina Rahman, Raianul Haque, Md. Sajjad Ul Hoque, Nishanm Chakrabarty, Mahmudul Hasan, Md. Mominur Rahman

ABSTRACT

Objectives: The present study was to investigate anti-nociceptive action of the methanol extract of Commelina benghalensis. Methods: The animals were submitted to acetic acid-induced writhing test and Formalin induced licking test to assess antinociceptive activities, respectively. Two doses 400 and 200 mg/kg were administered for testing. Results: The methanol extract of C. benghalensis at both doses, exhibited a significant (p < 0.05 - < 0.01) dose-dependent antinociceptive activity in acetic acid writhing test and Formalin test. In acetic acid-induced writhing test, oral administration of CB (200 and 400 mg/kg) also decreased the writhing significantly while compared to control. The dose 400 mg/kg showed maximum percentage of pain inhibition 52.24% and 64.29% for respectively. Diclofenac sodium (10 mg/kg) was used as reference antinociceptive drugs. Conclusions: The leaf extract has potential antinociceptive activity. The present study supports the use of C. benghalensis in different depressive states.

Keywords: C. benghalensis, anti-nociceptive, Acetic acid writhing test, Formalin.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More