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Abstract

A REVIEW ON TASTE MASKING A NOVEL APROACH OF NEW TRENDS FOR THE ABNOVIOUS DRUGS

Dipak Suresh Minde* and Ravindranath B. Saudagar

ABSTRACT

Acceptability of any dosage form are mainly depends over its taste i.e mouth feel. Drug molecule interacts with taste receotor on the tounge to give bitter, sweet or salty taste sensation when they interacts with taste sensation when they dissaolve in saliva. this sensation of the taste is the result of signal transduction from the receptor organs for taste commanly known as taste buds. in market there are number of pharmaceutical preparations available in which active are bitter in taste, the improved palatability in these products has propmted the devlopment of numerous formulations which improved performance and acceptability. the bitterness of preparation also leads to patient compliance. so masking of bitterness becomes essential. to overcome this problem many tecniques have been devloped to mask the bitter taste of drugs. Proven methods for bitterness reduction and inhibition have resulted in improved palatability of oral pharmaceuticals several aproaches like adding flavors and sweetness, use of lipoprotiens for inhibiting bitterness coating of drug with inert agents, microemulsions, multiple emulsion, viscosity modifiers, vesicles and liposomes, prodrug formation formation and inclusion and molecular complexes, solid despersion system and aplication of ion exchange system and aplication of ion exchange resins have been tried by the formulators to mask the unpleasant taste of the biiter drugs. the main objective of this review is to explore various methodologies for masking the taste of abnoxious drugs aplicationsevaluations and also the recent trends in taste masking technologies.

Keywords: Taste, taste masking, bitter drugs, taste buds, taste masking technology, evaluation.


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