WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

INSILICO IDENTIFICATION OF POTENT PPAR AGONISTS FROM Rheum Emodi PLANT COMPOUNDS

Dr. Radhika Ravindran* and Dr. Sudarsanam Dorairaj

ABSTRACT

PPARs are members of the nuclear hormone receptor super family that bind to specific DNA response elements as heterodimers with the retinoid X receptor. The endogenous activators of all members of the PPAR family are a variety of fatty acids, which suggests that the PPARs are highly involved in lipid metabolism. The role of PPAR in combating diabetes has provided us the rationale to carry out structure based drug design studies. Docking results of PPAR γ with emodin, chrysophanol and the drug glibenclamide are performed using Glide. The finding suggests that both the components of R.emodi could serve as PPAR-γ agonists.

Keywords: PPAR, Type 2 diabetes, Docking, Chrysophanol, emodin, agonists.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More