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Abstract

COMPARISON OF INTRAVAGINAL MISOPROSTOL ALONE AND IN COMBINATION WITH INTRACERVICAL FOLEY’S CATHETER FOR TERMINATION OF SECOND TRIMESTER PREGNANCY AT A TERTIARY CARE HOSPITAL IN CENTRAL RURAL INDIA

Dr. Deepti Shrivastava*, Dr. Virul Shrivastava, Dr. Tejal Vaidya, Dr. Zansher Khan Nazar

ABSTRACT

Introduction: Terminating a pregnancy in 2nd trimester is a bigger danger to both the mother and foetus as compared to a 1st trimester pregnancy. A majority of the abortions in 2nd trimester are carried out because of foetal abnormalities and sometimes maternal complications. Out of the different methods of termination, medical methods are believed to be safer and more effective as compared to the surgical approaches.Intravaginal misoprostol and intracervical Foley’s catheter are the most preferred methods amongst which some researchers claim intravaginal misoprostol whereas others believe intracervical Foley’s catheter to be more effective and few researches have speculated that the 2 methods combined give best results. Materials & Methods: The study was carried out in 40 patients of AVBRH, Sawangi(M) after taking consent from ethical committee. Subjects were divided into 2 groups according to the method used for termination of pregnancy either misoprostol alone(n=20) or combined method(n=20). Primary and secondary outcomes and side effects were compared amongst the 2 groups. P value of less than 0.05 was considered statistically significant. Result: The induction to abortion interval was 7.8±2.2 hours in combined group which is significantly shorter than misoprostol alone group (12.95±1.55 hours) (p<0.05). The success rate was higher in combined group (90%) as compared to misoprostol (80%). Conclusion: Use of intracervical Foley’s catheter improves the efficacy of intravaginal misoprostol for 2nd trimester abortions with shorter induction to abortion period with no significant side effects.

Keywords: Efficacy, Foley’s catheter, Intravaginal, misoprostol, pregnancy, 2nd trimester, termination.


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