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Abstract

REVIEW ARTICLE ON GLYCOGEN STORAGE DISEASES

*Dr. Rafia Bano

ABSTRACT

Glycogen serves as the primary fuel reserve for the body's energy needs. Glycogen storage diseases, also known as glycogenoses, are genetically linked metabolic disorders that involve the enzymes regulating glycogen metabolism. Symptoms vary by the glycogen storage disease (GSD) type and can include muscle cramps and wasting, enlarged liver, and low blood sugar. Disruption of glycogen metabolism also affects other biochemical pathways as the body seeks alternative fuel sources. Accumulation of abnormal metabolic byproducts can damage the kidneys and other organs. GSD can be fatal, but the risk hinges on the type of GSD.

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