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Abstract

EVALUATION OF 5-((E)-4-((E)-3-(4-(DIMETHYLAMINO)PHENYL)-3- OXOPROP-1-EN-1-YL)BENZYLIDENE)THIAZOLIDINE-2,4-DIONE AS A α-GLUCOSIDASE INHIBITOR'

Dr. Ch. Prasad,*, Dr. Y. Srinivasa Rao and A. Kanakaraju

ABSTRACT

In the present study a 2,4-thiazolidinedione derivative 5-((E)-4-((E)-3- (4-(dimethylamino)phenyl)-3-oxoprop-1-en-1- yl)benzylidene)thiazolidine-2,4-dione (1) has been studied for its α- glucosidase inhibitory potential. The results clearly state that this compound is a potent inhibitor of α-glucosidase enzyme. This observation is remarkable starting point to develop potential inhibitors of α-glucosidase enzyme.

Keywords: 2,4-Thiazolidinedione, Alpha-glucosidase (?- glucosidase).


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