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Abstract

ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF ISOLATED STIGMASTEROL FROM METHANOL EXTRACT OF ACALYPHA INDICA

G. Venkateshwarlu* and N. L. Gowrishanker

ABSTRACT

Isolated stigmasterol from methanolic solvent extract of acalypha
indica were tested for antidiabetic activity and antioxidant activity
using streptozocin induced diabetic rats compared with standard and
DPPH method for antioxidant activity. the results expressed that
stigma sterol has significant protection and maximum reduction in
blood glucose was observed in streptozocin induced diabetic rats.in
DPPH method maximum antioxidant showing the freeradical
scavenging activity of DPPH .the result of this comprehensive study
reveal that Isolated stigmasterol acalypha indica methanol extract
shown stastically significant antidiabetic activity comparison to the standard glibenclamide.

Keywords: Acalypha indica, antidibetic activity, streptozocin induced method, Antioxidant acivity, DPPH method.


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