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Abstract

CLINICAL STUDY TO VALIDATE THE THE EFFICACY AND SAFETY OF UNANI FORMULATION IN MENOPAUSE

Dr. Sofia Naushin*, Dr. Mubarak Ali and Dr. Aysha Raza

ABSTRACT

“Sinne ya’s” (Menopause) which means period of Zamane naumaidee (hopeless period). According to unani physician the whole human body is divided in to four age groups, which are consider to carry their particular mizaj. The age group of 35-60 years is known as sinne kahulat in which mizaj becomes barid (cold) and yabis (dry). It is believed that, Ehtebaz haiz (stoppage of menses) in women of this age occurs naturally due to change of mizaj. In Modern system of medicine, Menopause, a natural step in the aging process, represents the end of menstruation after the last menstrual period in the previous 12 months. The World Health Organization has defined the menopause as the permanent cessation of menstruation resulting from loss of ovarian follicular activity (World Health Organization, 1996). As the ovaries becomes less functional they produce less of these hormones and body responds accordingly. Primary menopausal symptoms are considered to be the vasomotor symptoms, referring to hot flushes and night sweats. The vasomotor symptoms may also be associated with sleep and mood disturbances, as well as decreased cognitive function. Other menopausal symptoms are urogenital atrophy, urinary tract infections and incontinence, somatic symptoms, sexual dysfunction and decreased libido, and loss of skin elasticity. The treatment strategy of menopausal syndrome has been to replace the deficient oestrogen. This strategy of hormone replacement has got alarming physical hazards. Phytoestrogen are naturally occurring plant compounds that are similar in some ways to estradiol, the most potent naturally occurring estrogen. The unani formulation in the study was effective and safe than placebo for ameliorating somatic, psychological and urogenital symptoms at post intervention the thereby improving HRQoL.

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