Abstract

CLINICAL STUDY TO VALIDATE THE THE EFFICACY AND SAFETY OF UNANI FORMULATION IN U.T.I (E-coli induced)

Dr. Mubarak Ali*, Dr. Sofia naushin and Dr. Shahnawaz Ali

ABSTRACT

Urinary tract infection (UTI) refers to both microbial colonization of the urine and tissue invasion of any structure of the urinary tract, or the presence in an appropriately collected mid stream specimen of urine (MSU) of more than colony forming units per ml of urine. UTI occurs predominantly in females specially during the child bearing age. Its incidence among school girls is 1-2 %. It is only 0.03% in boys of the same age. Also the incidence in females rises about 1% per decade. Gram -ve bacteria E-coli is most commonly responsible, although yeast, fungi and viruses may produce UTI. In unani literature there is no specific term coined for Urinary tract infection. But the aetiopathogenesis, clinical features and managements have been described by most of the Unani Physicians under different heading i.e. Warm-e-kuliya, Warm-e-masana, Hurqat-e-baul and Taqtir-ul-baul. The general guidelines for the management of urinary tract infection (Tadia-majra-e-baul) in unani system of medicine include, use of anti- inflammatory drugs, excretion of rotten humour and use of diuretics. The unani drugs being safe, efficacious, easily available, cost effective and above all free from after effects of medications can play an important role in eradication of this problem if properly researched. Unani system of medicine uses holistic approach, the trial drug shows significant improvement overall in symptoms & signs and laboratory findings of the disorder as well as when compared to the standard control group. The formulation was found effective and completely safe in Urinary tract infection.

Keywords: Warm-e-kuliya, Warm-e-masana, Hurqat-e-baul and Taqtir-ul-baul.