WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

AN IMPROVED AND CONVENIENT ROUTE FOR THE SYNTHESIS OF 5-METHYL-1H-TETRAZOL-1-YL SUBSTITUTED BENZENAMINES

Suresh G. Vedpathak*, R. G. Momle, Gopal K. Kakade and Vilas S. Ingle

ABSTRACT

An improved and convenient route for the synthesis of a series of 5-
methyl-1H-tetrazol-1-yl substituted benzenamines have been reported
via multi-step reactions from nitroanilines. 1, 5-Disubstituted tetrazole
containing nitrobenzenes 3 have neen synthesized from
nitroacetanilides 2 by reacting with sodium azide in the presence of
titanium tetrachloride as a catalyst. The reduction of 1, 5-disubstituted
tetrazole containing nitrobenzenes 3 which on using NaBH4 gives 5-
methyl-1H-tetrazol-1-yl substituted benzenamines 4 in good to
excellent yields.

Keywords: Benzenamines, Reduction, Tetrazoles, Titanium tetrachloride.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More