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Abstract

TO STUDY SEROPREVALENCE AND VARIOUS RISK FACTORS ASSOCIATED WITH HCV IN HEPATIC DISORDERS

*Manika Mehta and Bhavna Singla 

ABSTRACT

Background: HCV is the major factor in the development of hepatic disorders. Aim: To study seroprevalence of HCV in liver disorders and risk factors associated with liver disorders and HCV. Material and Methods: The study was conducted on 100 patients of hepatic disorders admitted in Medicine wards of Rajindra Hospital, Patiala. Detailed history was taken with special emphasis on risk factors like blood transfusion, alcohol, drug addiction, needle-injury, multiple sexual contacts and perinatal transmission. Then blood was tested for Anti HCV abs. Results: Seroprevalence of HCV in patients with hepatic disorders was 40%. Out of 40, 35 were males and 5 were females with a male to female ratio of 7: 1. Majority of males were in the age group of 41-60 years followed by the age group of 21-40 years. Maximum number of anti-HCV positive cases had blood transfusion as a risk factor. Seroprevalence of HCV in patients with drug addiction (81.8%), blood transfusion (48%) and HCC (50%). Conclusions: Great stress must be laid on proper preventive measures such as screening of blood, safe sexual practices, proper sterilization of instruments, proper disposal of contaminated material.

Keywords: HCV (Hepatitis C virus), Prevalence, HCC (Hepatocellular carcinoma).


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