WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

A STUDY ON PREVALENCE ,MICROBIOLOGICAL PROFILE AND ANTIBIOTIC SENSITIVITY OF CARBAPENEM RESISTANT ENTEROBACTERIACEAE IN A TERTIARY CARE ICU SETTINGS.

Rohey Jan*, Waseem Raja, Nita George, Mohan Mathew, Molly Johny, Vipin Lal, George Paniker

ABSTRACT

Objective: The emergence of Carbapenem Resistant Enterobacteriaceae (CRE) in recent times has become a serious threat to public health due to the high mortality, potential dissemination rates and limited availability of effective treatment options. Aims/objective: The aim of the study was to determine the prevalence rate of CRE in ICU settings at Lakeshore hospital & research centre kochi–Kerala. Methods: A Retrospective study was conducted in Critical care department over a period of 1 year from January 2015 – December 2015, following its approval by the institutional ethical committee. A total of 1035 susceptible isolates were retrieved from the electronic medical records (EMR) of the hospital. The study sample includes patients from all ICU,s and specimens tested for culture sensitivity were blood, urine, endotrachial aspirate, sputum, wound pus/ abscess and others. Results: The total number of Enterobacteriace isolates were 624 (60.3%), out of which CRE isolates were 50, with CRE Prevelance rate of 8.0%, (50/624). The most common organisms identified were Klebsella pneumoniae 82% followed by E. Coli 18% & the most common sources of CRE isolates were ET aspirates (22%), followed by urine culture (18%). Majority of the CRE isolates were found in age group of 61-75 years (42%), followed by 46-60 yrs (24%) with male prepondance (2.1:1). CRE isolates were mainly sensitive to Tigecycline (70%), Colistin (50%) and amikacin (40%). Conclusion: This study provides a baseline data of current scenario of CRE in our set up. A strict antibiotic policy should be addressed especially with observed emergence of carbapenem resistance. Continuous review of need to invasive devices and strict compliance with basic infection control measures are mandatory to limit the spread of CRE.

Keywords: .


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More