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T. Boopathi*, K. Gopalasatheeskumar, S. Parthiban, G. Sangeetha, M. Thanga Kokila and T. Manimaran


In the present study, the antimicrobial activity of leaves of Tecoma stans and Muntingia calabura were performed by using disc diffusion method. The antimicrobial activity of the extracts were studied in different concentrations against Eight pathogenic bacterial strains, three Gram-positive (Staphylococcus aureus, Streptomyces filvissimus, Basillus subtilis) and five Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, proteus mirabilis, shigella flexneri) and two fungal strains (Aspergillus niger & Candida albicans). These strains have been selected for the basis of its application purpose of further formulation study. The ethanolic extract of Tecoma stans was found to be active on most of the clinically isolated microorganism and fungi, as compare with standard drugs. The activities of these extracts are found to be quiet comparable with the standard antibiotics screened under similar conditions. So these extracts can be used as an external antiseptic in prevention and treatment of bacterial infections. The present study justified the claimed uses of leaves in the traditional system of medicine to treat various infectious disease caused by the microbes.

Keywords: Tecoma stans, Muntingia calabura, Disc diffusion method, Antimicrobial, Ethanolic extract.

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