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Vaidya Meenakshi Rewdkar Kole*


Psoriasis has become most emerging disease in recent era. In past, its incidence rate was 1-2% which in recent decades has increased to 2- 4%. The exact etiological factor for disease is not yet known. Psoriasis is generally thought to be a genetic disease which is triggered by environmental factors. In recent studies histocompatibility antigen is found in psoriatic patients, hence immuno-modulator drugs like cyclosporine are thought to be effective in these patients. It has approximately 40% heridatory prevalence. It is characterized by chronic, papulosquamous, recurrent, erythematous papules which can occur at any age and the symptoms get exaggerated in cold climates and decrease in hot climate. Treatment of Psoriasis depends on the type, location and extent of the disease. Topical glucocorticoids, Immunosuppressants like Methotrexate, Cyclosporine and phototherapy like Ultraviolet light are used. They are to some extent hepatotoxic, nephrotoxic and have adverse effects on bones and haemopoesis. As psoriasis is a chronic disorder, these drugs are to be taken for longer duration which hampers the life of the patient.

Keywords: psoriasis, mahavastu, matsyashakalopama, tridosha, ekakushtha.

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