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Abstract

SYNTHESIS AND CHARACTERIZATION OF A SERIES OF NOVEL SCHIFFS’ BASES OF 1, 3, 4- THIADIAZOLE DERIVATIVES

Gnanam T. and Dr. V. Niraimathi*

ABSTRACT

Literature review showed that 1, 3, 4- Thiadiazole and its derivatives possess wide range of therapeutic effectiveness. In addition, Schiffs’ bases also possess broad spectrum anticancer, antibacterial, antifungal and anti-inflammatory activities. Keeping in view of the need for development of novel antimicrobial drugs to combat with the Super bugs developed due to resistance for old drugs, an attempt has been made to develop a series of novel Schiffs’ bases of 1,3,4- Thiadiazole derivatives. So they were synthesized and characterized using IR, NMR and mass spectra.

Keywords: Synthesis, Characterization, Schiffs’ base, 1, 3, 4-Thiadiazole derivatives.


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