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Abstract

HYPOGLYCEMIC ACTIVITY OF LEAVES AND CALLUS OF MEMECYLON UMBELLATUM IN ALLOXAN INDUCED DIABETIC RAT MODEL

Anbukkarasi M.* and Dhamotharan R.

ABSTRACT

Diabetes mellitus is a predominant risk factor for the development of
cardiovascular, nephropathy, opthalamic, obesity, hepatic and many
more associated diseases. Many chemical drugs in market has proven
effective in reducing blood glucose levels, but also lead to many
damages due to years for continuous medication. To reduce these side
effects, the current research concentrates on the ethnobotanical
prototype of using leaves and callus to reduce diabetic levels in the
alloxan induced rodent model. The leaves of callus proved very
effective in reducing blood glucose levels of treatment groups than in
comparison to induced diabetic control and vehicle groups. Thus,
ethnobotanical approach can pave a new approach in the field of drug discovery.

 

Keywords: Callus, Diabetes mellitus, alloxan induced rodent model. Blood glucose levels.


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