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Amandeep Singh* and Narinder Singh


Electrospun nonwoven nanofibers are rising as a novel dosage form for multipurpose treatment adjacent to sexually transmitted infections, including HSV, Controlled release systems have beneficial for the health management, release of formulation for life science application and tissue engineering scaffolds. Nonwoven structures are used widely in health system because of their great surface area; many more properties are process cost effectiveness, absorbable, simplistic processing. For water loving small molecule drugs, their high water solubility and poor partition and uneven compatibility with mysterious polymers make it long term release yet more challenging. At this point explore several strategy to continue release of water loving small molecule drugs that are highly loaded in electrospun fibres. Various drug-incorporation techniques with the help of electrospinning like blending, co-axial electrospinning. Types of polymers used in sustained release of drug and effect of polymer on drug release. Strategy for sustained drug release from electrospun fibres and their release mechanism.

Keywords: Nanofiber, Drug release mechanism, Technique, Application.

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