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Abstract

AN OVERVIEW OF A GASTRO-RETENTIVE FLOATING DRUG DELIVERY SYSTEM

* Pravin K. Bhoyar1, Jagdish R. Baheti 2, Vishal V. Burde 3

1Department Of Pharmaceutical Sciences, NIMS University, Jaipur, Rajastan, India
2Shriman Suresh Dada Jain College of Pharmacy, Chandwad, Nasik, Maharashtra, India.
3Sonekar college of pharmacy, Koradi, Dist: Nagpur, Maharashtra, India.

ABSTRACT

A lot of scientific and technological advancements have been made in the drug delivery research in the recent years. Physiological problems like short Gastric Residence Time (GRT) and the unpredictable Gastric Emptying Time (GET) were overcome with the use of floating dosage forms which provide opportunity for both local and systemic drug action. Several approaches are currently being used to prolong the GRT, including floating drug delivery systems (FDDS), also known as hydrodynamically balanced systems (HBS), swelling and expanding systems, high-density systems, and other delayed gastric emptying devices. In this review, the current and recent developments of FDDS, including patented delivery systems and marketed products, are discussed.

Keywords: Gastric residence time; Gastroretentive systems; Floating drug delivery system; Effervescent; non-effervescent.


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