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Abstract

INHIBITION OF LOW DENSITY LIPOPROTEIN OXIDATION AND PROTECTION OF DNA CLEAVAGE BY PHENOLIC EXTRACT FRACTION OF OCIMUM BASILICUM

P. Karthiga and M. Bimonisha, Dr. A. Chandra Mohan* and K. Nisha

ABSTRACT

The medicinal plant of Ocimumbasilicum leave have the valuable plant constituents for the scavenging of free radicals because of their phenolic hydroxyl groups. That the amount of polyphenolic compounds increases, the antioxidant activity also increases. The present study demonstrates that the polyphenolic extract of Ocimumbasilicum leave scan protect the body from oxidative stress from ROS, which may be due to the phyto-chemicals in the form of polyphenols that occur in the plant. However, additional studies are necessary to develop a method for the fractionation and identification of polyphenols and to determine the most active antioxidant compounds in the polyphenolic extract free radical scavenging assay were carried out.

Keywords: Antihemolytic, methanolic extract, hLDL, H2O2 and NA.


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