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Abstract

DIFFERENCE IN METHOD OF MANUFACTURING OF CHYAVANAPRASA AMONG GMP CERTIFIED COMPANIES IN KERALA

Mahesh S.*, Jacob M. Titus, Sheela Karalam B., Rajmohan V., Aravind S. and Neethu S. Pillai

ABSTRACT

Background: Chyavanaprasa is one among the popular Ayurvedic preparations grouped under Rasayana, which incorporates more than forty botanicals. In order to ensure quality, safety and efficacy of Ayurvedic formulations available in the market like Chyavanaprasa, uniform method of preparation must be adopted by different GMP certified companies. Aim: The present study was carried out to find out the variations adopted in the method of preparation of Chyavanaprasa by various GMP certified companies in the state of Kerala. Methodology: The study comprises a survey in eight GMP Certified companies having production above 4000 kg per annum for the formulation. Data collection was carried out by interview using a questionnaire given to specific personnel in the companies and direct observation of the various processes associated with and related to the production of Chyavanaprasa. Results: The survey reveals the existence of difference in method of preparation of Chyavanaprasa among GMP Certified companies and this is also different from API recommendations for the preparation of Chyavanaprasa. Conclusion: The result confirms the existence of non-uniformity in the production of Chyavanaprasa among various companies. Hence development of standard operating procedures in the production of Chyavanaprasa by considering the recommendation of API is necessary for quality assurance of the formulation in the Kerala market.

Keywords: Avaleha, Chyavanaprasa, Good Manufacturing Practices, Rasayana, Quality assurance.


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