Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF VIJAYSARADI GHANVATI: AN EFFECTIVE FORMULATION FOR THE MANAGEMENT OF TYPE 2 DIABETES (MADHUMEHA)

Sachin Kumar Sharma*, Alankruta R. Dave, Harisha C.R., Shukla V. J., Vasundhara Sharma

ABSTRACT

Diabetes Type 2 (Madhumeha) is one of the most serious health problem in the 21st century. According to the World Health Organization (WHO) report, India today heads the world with over 32 million diabetic patients and this number is projected to increase to 79.4 million by the year 2030.[1] Diabetes is likely to continue to be a leading cause of morbidity and mortality in the near future. Lots of single and compound drugs have been described in Ayurveda for the management of Madhumeha. Vijaysaradi Kwath is one of them and it is very effective in the Madhumeha. Kwath is bitter in taste and patients have to prepare kwath each time which takes lot of time. To overcome these above problems along with the problems of palatability, feasibility, shelf life with the kwath form of drug, an effort is made to convert it into vati form i.e. Vijaysaradi Ghanvati. This paper is made to standardize the formulation through Pharmacognostical and Pharmaceuticals measures. The compound was analyzed and standardized scientifically through qualitative and quantitative analysis by physico-chemical parameters and High Performance Thin Layer Chromatography (HPTLC) and pharmacognostical measures. Pharmacognostical analysis showed characteristics of all the ingredient drugs in the tablet. In Pharmaceuticals analysis, HPTLC was done in appropriate solvent system in which 6 and 5 spots were distinguished at 254 nm and 366 nm respectively. This study may be used as reference standard in the further researches.

Keywords: Diabetes Type 2 (MADHUMEHA), Pharmaceuticals, Pharmacognostical, Vijaysaradi Ghanvati.