WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

A CROSS SECTIONAL STUDY IN NORTH EASTERN UTTAR PRADESH POPULATION FOR THE ESTIMATION OF BMI, HDL & TRIGLYCERIDES LEVELS IN RECENTLY DIAGNOSED PATIENTS WITH TYPE 2 DIABETES MELLITUS TAKING METFORMIN ALONE, METFORMIN WITH ADD ON SITAGLIPTIN AND SITAGLIPTIN

*Neerjesh, Vipender Singh Chopra, Raj Kishore Singh, Rakesh Chandra Verma, Praduman Mall and Gyanendra Kumar Bind

ABSTRACT

Objectives: To evaluate the role of Metformin, Sitagliptin & combination of both drugs in Body weight, HDL-C & Triglyceride levels in recently diagnosed patients of type 2 Diabetes mellitus. Methods: This cross-sectional study includes analysis of total 75 patients divided in 3 groups. Metformin group (2000 mgs), Sitagliptin group (100 mgs), Combination of both Metformin & Sitagliptin group (Metformin 1000 mg+ Sitagliptin 50 mg). Their body weight (BMI) & Laboratory investigations regarding HDL & Triglycerides were carried out and findings were noted in each follow-ups. Results: After 24 week onwards there were statistically significant reduction in BMI in each group but the in 3rd group (Combination group) the reduction in BMI was Most highly significant (p<0.001). On other hand HDL level was raised significantly (p<0.01) in all the three groups but in the Sitagliptin and combined group it was most highly significant (p<0.001) observed from 24 week onwards, whereas in Triglyceride levels, Metformin and Sitagliptin, both group of patients showed significant (p<0.01) reduction. Metformin group showed significant (p<0.01) reduction earlier at 12 week and Sitagliptin showed significant reduction (p<0.01) later at 36 week. In the combined group it was insignificantly (p>0.05) fluctuating. Conclusions: In conclusion, significant differences was found in effects of Sitagliptin treatment on body weight (BMI) & HDL, Triglycerides level in patients recently diagnosed with type 2 Diabetes mellitus.

Keywords: Type 2 diabetes mellitus, Body weight, HDL-C, Triglycerides, Metformin, Sitagliptin.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More