WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

ANALYSIS OF ANTIBACTERIAL ACTIVITY OF THE LEAVES OF GOSSYPIUM HIRSUTUM ON SELECTED BACTERIA

Nwobodo H. A.*

ABSTRACT

Antibacterial and phytochemical analysis of the leaves of Gossypium
hirsutum was carried out using selected bacteria; Salmonella typhi,
Staphylococcus aureus, Proteus mirabilis and Escherichia coli. The
leaves were collected, identified, washed and air dried at room
temperature and milled into powder. Forty (40) g of the powder was
macerated in extracting solvents (methanol and ethanol) used. The
crude extract was concentrated by evaporation at various
concentrations (100mg/ml, 300mg/ml, and 500mg/ml) prepared using
5% DMSO. Phytochemical analysis showed that Saponin (+++),
Tannin (+++), Alkaloids (+++), and Flavonoids (+) were present.
Methanol and ethanol yielded 220mg (0.55%) and 150mg (0.38%)
crude extracts respectively. Methanol extract at 500mg/ml exhibited
inhibition zones of 28 mm, 28 mm, 26 mm, and 20 mm against Escherichia coli, Salmonella
typhi, Proteus mirabilis and Staphylococcus aureus respectively while ethanolic extract
showed inhibition zones of 20 mm, 17 mm, 17 mm, and 7 mm against Escherichia coli,
Salmonella typhi, Proteus mirabilis and Staphylococcus aureus. Both extracts showed
activity against all the test bacteria except Staphylococcus that was less susceptible to
ethanolic extract. This study therefore suggests that methanolic and ethanolic extracts of
Gossypium hirsutum have activity against certain bacteria since they exhibited comparable
activity with the positive control (ciprofloxacin). Further research should be conducted to
isolate, purify and characterize bioactive component of the extracts responsible for the
observed antibacterial activity.

Keywords: Antibacterial activity, leaf extract, Gossypium hirsutum, Bacteria.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More