WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

FORMULATION AND INVITRO EVALUATION OF BIOADHESIVE BILAYERED BUCCAL TABLETS OF ENALAPRIL MALEATE

Vineela Sangu* and H. Padmalatha

ABSTRACT

In the present study bilayer buccal tablets were formulated by using ethyl cellulose as backing membrane. From the foregoing investigation it may be conclude that the release rate of drug from the buccal tablets can be governed by the polymer and concentration of the polymer employed in the preparation of tablets. Regulated drug release in first order manner attained in the current study indicates that the hydrophilic matrix tablets of enalapril maleate was prepared using carbopol 934 and HPMC K100 can successfully be employed as a buccoadhesive controlled released during delivery system. The pre compression blend for all formulations was subjected to various evaluation parameters and the results were found to be within limits. The post compression parameters for all the formulations also found to be within limits. Slow, controlled and complete release of enalapril maleate over a period of 9 hours was obtained from matrix tablets formulated employing HPMC K 100 (F5 Formulation) with 93.45 % drug release.

Keywords: Bilayer buccal tablet, Enalapril maleate, HPMC, Carbopol.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More