WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SCREENING OF LEAF EXTRACTS OF ARGEMONE MEXICANA FOR IT’S ANTIARTHRITIC ACTIVITY IN EXPERIMENTAL ANIMALS

Amita Tilak, Ranjana Sharma, R. N. Thakur, Sudhir Singh Gangwar and Ravindra C. Sutar*

ABSTRACT

The main objective of the work was to evaluate the use of Argemone m exicana (AM) leaves forit’santiarthritic activity by using petroleum eth er (PEAM) and methanolic (MAM) extract of Argemone mexicana (AM) leavesincomplete Freund’s adjuvant (CFA) model. The ntiarthritic activity of different doses of AM extract (100 and 300 mg/kg) in rats were evaluated on 7th, 14th and 21st day of treatment. The paw volume displacement, secondary lesions changes were measured, as a mark of antiarthritic activity. The AM extracts at the dose of 100 and 300 mg/kg showed significant reduction in paw volume on 7th, 14th and 21st day of treatment. Methanolic extract was more significant than petroleum ether extract and showed dose dependenteffect.Methanolic extract was more potent than petroleum et her extract for showing antiarthritic activity.The results indicate thatme thanol extracts and petroleum ether extracts contained chemical constituents of the leaf extract such as isorhamnetin-3-O-β-Dglucopyanoside, β-amyrin, cysteineand phenylalanine which might be responsible for such activity in case of Complete Freund’s Adjuvant induced arthritis.

Keywords: Antiarthritic, Complete Freund’s Adjuvant, Argemone Mexicana.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More